This course introduces students to the nomenclature, concepts, and basic skills of quantitative risk assessment (QRA). The goal is to provide an understanding necessary to read and critically evaluate and perform QRA. Emphasis is on the intellectual and conceptual basis of risk assessment, particularly its dependence on toxicology, epidemiology, and exposure assessment. Quantitation of exposure and dose response provides practical skills and theoretical background, although not detailed in mathematical and model derivations. Specific cases consider the use of risk assessment for setting occupational exposure limits, establishing community exposure limits, and quantifying the hazards of environmental exposures to chemicals in air, drinking water, consumer products, and the built environment.
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